Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ULKL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | ULKL1 |
| Chromosome | 22q12.1 |
| Protein Type | Kinase |
| Function | is a human gene encoding a serine/threonine protein kinase related to the well-characterized ULK1 and ULK2 proteins. |
| Primary Expression | most tissues including heart, liver, kidney, and muscle |
| Molecular Weight | 52 kDa |
| Amino Acids | 472 aa |
| Exons | 14 |
| Ensembl ID | ENSG00000038002 |
| GeneCards | ULKL1 |
| Human Protein Atlas | ULKL1 |
| Brain | Moderate expression throughout the brain, including in cortex, hippocampus, and cerebellum. |
| Peripheral Tissues | Expressed in most tissues including heart, liver, kidney, and muscle. |
| Cellular Localization | Primarily cytoplasmic, associated with various cellular membranes. |
| Neuronal Compartments | Present in neuronal cell bodies and dendritic processes. |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
ULKL1["ULKL1"]
neurodegeneration["neurodegeneration"]
ULKL1 -->|"implicated_in"| neurodegeneration
style ULKL1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ULKL1 in their description or question text
No additional research found