gene

TRPM1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TRPM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

0Outgoing

1Incoming

0Experiments

0Debates

Summary

Page for TRPM1 Gene

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🧬 Gene Info

Gene Symbol	TRPM1
Full Name	Transient Receptor Potential Cation Channel Subfamily M Member 1 (Melastatin-1)
Aliases	Transient Receptor Potential Cation Channel Subfamily M Member 1
Chromosome	15q21.2
Protein Type	Channel
Function	### Visual Processing
Primary Expression	ON-bipolar cells where it: - Receives synaptic input from photoreceptors via glutamate release - Generates depolarizing responses to light onset (ON r
Molecular Weight	213 kDa
Amino Acids	1865 aa
Exons	27
UniProt ID	Q9Y5H5
NCBI Gene ID	4300
Ensembl ID	ENSG00000144306
OMIM	603446
GeneCards	TRPM1
Human Protein Atlas	TRPM1
Associated Diseases	neurodegeneration
KG Connections	1 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: TRPM1 — AlphaFold Q9Y5H5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

flowchart TD
    N0["TRPM1"]
    N1["mGluR6"]
    N1 -->|"regulates"| N0
    N2["neurodegeneration"]
    N0 -->|"implicated in"| N2

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 protein

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
mGluR6	regulates	protein	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TRPM1 in their description or question text

No additional research found