protein

TMEM9PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TMEM9PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

The TMEM9 protein participates in cellular trafficking pathways and has been shown to interact with the vacuolar protein sorting 34 (VPS34) complex, a key regulator of autophagosome formation.

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🔬 Protein Info

Gene Symbol	TMEM9PROTEIN
Protein Family	TMEM family
Function	is a small multispan membrane protein localized primarily to the endoplasmic reticulum (ER) and Golgi apparatus.
Subcellular Localization	primarily to the endoplasmic reticulum (ER) and Golgi apparatus
Molecular Weight	19 kDa
Amino Acids	163 aa
UniProt ID	Q9BSG7
GeneCards	TMEM9PROTEIN
Human Protein Atlas	TMEM9PROTEIN
ER-Golgi Trafficking	The protein likely functions in vesicle transport between ER and Golgi compartments
Nutrient Sensing	Through autophagy modulation, TMEM9 participates in cellular energy and nutrient homeostasis
Protein Quality Control	By supporting autophagy, TMEM9 helps clear misfolded proteins and damaged organelles
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: TMEM9PROTEIN — AlphaFold Q9BSG7 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

tmem9-protein

protein · 1933 words

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Pathway Diagram

graph TD
    TMEM9PROTEIN["TMEM9PROTEIN"]
    neurodegeneration["neurodegeneration"]
    TMEM9PROTEIN -->|"implicated_in"| neurodegeneration
    style TMEM9PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TMEM9PROTEIN in their description or question text

No additional research found