Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TENASCINC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | TENASCINC |
| Full Name | Tenascin C |
| Protein Family | Tenascin family |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | injury, inflammation, and cancer |
| Molecular Weight | 240-320 kDa |
| Pathways | Wnt |
| UniProt ID | P24821 |
| GeneCards | TENASCINC |
| Human Protein Atlas | TENASCINC |
| Extracellular matrix | Modulates ECM organization |
| Associated Diseases | neurodegeneration |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["TENASCINC"]
N1["Wnt"]
N0 -->|"associated with"| N1
N2["Macrophage"]
N0 -->|"associated with"| N2
N3["Integrin alphavbeta1"]
N0 -->|"binds"| N3
N4["FAK"]
N0 -->|"activates"| N4
N5["neurodegeneration"]
N0 -->|"implicated in"| N5
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 pathway| Target | Relation | Type | Str |
|---|---|---|---|
| Wnt | associated_with | pathway | 0.80 |
| Macrophage | associated_with | cell_type | 0.80 |
| Integrin αvβ1 | binds | receptor | 0.70 |
| FAK | activates | enzyme | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TENASCINC in their description or question text
No additional research found