Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TENASCIN C: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | TENASCIN C |
| Molecular Weight | 320 kDa |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
graph TD
TNC["TENASCIN C"]
CSF["Compact Spheroid Formation"]
HER2["HER2"]
ECM["Extracellular Matrix Remodeling"]
INFL["Neuroinflammation"]
ASTRO["Astrocyte Activation"]
MICRO["Microglial Activation"]
SCAR["Glial Scar Formation"]
REGEN["Axonal Regeneration"]
PLAS["Synaptic Plasticity"]
NEUR["Neuronal Death"]
PROT["Neuroprotection"]
CYTO["Cytokine Release"]
ANGIO["Angiogenesis"]
BBB["Blood-Brain Barrier Disruption"]
TNC -->|"mediates"| CSF
TNC -->|"causes"| HER2
TNC -->|"promotes"| ECM
TNC -->|"activates"| ASTRO
TNC -->|"stimulates"| MICRO
ASTRO -->|"produces"| TNC
MICRO -->|"secretes"| CYTO
TNC -->|"facilitates"| SCAR
ECM -->|"inhibits"| REGEN
SCAR -->|"blocks"| REGEN
TNC -->|"disrupts"| PLAS
INFL -->|"leads to"| NEUR
TNC -->|"promotes"| ANGIO
TNC -->|"causes"| BBB
HER2 -->|"can promote"| PROT
classDef central fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#ffffff
classDef pathological fill:#3a1a1a,stroke:#ef5350,stroke-width:2px,color:#ffffff
classDef protective fill:#1a3a2a,stroke:#81c784,stroke-width:2px,color:#ffffff
classDef regulatory fill:#2a1a3a,stroke:#ce93d8,stroke-width:2px,color:#ffffff
class TNC central
class CSF,SCAR,BBB,NEUR,INFL pathological
class REGEN,PLAS,PROT,ANGIO protective
class HER2,ASTRO,MICRO,ECM,CYTO regulatory| Target | Relation | Type | Str |
|---|---|---|---|
| Compact Spheroid Formation | mediates | phenotype | 0.85 |
| HER2 | causes | concept | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TENASCIN C in their description or question text
No additional research found