gene

SUV39H1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SUV39H1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

1Hypotheses

1Analyses

2Outgoing

0Incoming

0Experiments

4Debates

Summary

SUV39H1

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🧬 Gene Info

Gene Symbol	SUV39H1
Full Name	Suppressor of Variegation 3-9 Homolog 1
Chromosome	Xp11.23
Function	is a human gene
UniProt ID	O43463
Ensembl ID	ENSG00000101945
OMIM	300254
GeneCards	SUV39H1
Human Protein Atlas	SUV39H1
Associated Diseases	neurodegeneration
KG Connections	2 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: SUV39H1 — AlphaFold O43463 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SUV39H1

gene · 1151 words

→

Pathway Diagram

graph TD
    SUV39H1["SUV39H1"]
    neurodegeneration["neurodegeneration"]
    SUV39H1 -->|"implicated_in"| neurodegeneration
    style SUV39H1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (2)

Target	Relation	Type	Str
retrotransposon expression	inhibits	process	0.70
heterochromatin maintenance	regulates	process	0.70

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
SUV39H1 Restoration Represses Aberrant Transposon Expression	0.620	neurodegeneration	Investigate mechanisms of epigenetic rep

Mentioning Analyses (1)

Scientific analyses that reference this entity

Investigate mechanisms of epigenetic reprogramming in aging neurons, including D

neurodegeneration | 2026-04-10 | 7 hypotheses Top: 0.700

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (4)

Multi-agent debates referencing this entity

Investigate mechanisms of epigenetic reprogramming in aging neurons, including D

closed · Rounds: 4 · Score: 0.50 · 2026-04-21

Investigate mechanisms of epigenetic reprogramming in aging neurons, including D

closed · Rounds: 0 · Score: 0.48 · 2026-04-21

Investigate mechanisms of epigenetic reprogramming in aging neurons, including D

closed · Rounds: 0 · Score: 0.51 · 2026-04-21

Investigate mechanisms of epigenetic reprogramming in aging neurons, including D

closed · Rounds: 4 · Score: 0.73 · 2026-04-21

Related Research

Hypotheses and analyses mentioning SUV39H1 in their description or question text

No additional research found