Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about STRADA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | STRADA |
| Full Name | STE20-Related Kinase Adaptor Alpha |
| Chromosome | 17q22 |
| Protein Type | Kinase |
| Function | STRADA encodes a STE20-related kinase adaptor protein that acts as a regulatory component of the mTORC1 pathway. |
| Pathways | mTOR, AMPK |
| UniProt ID | Q7Z417 |
| NCBI Gene ID | 92335 |
| Ensembl ID | ENSG00000120289 |
| OMIM | 614556 |
| GeneCards | STRADA |
| Human Protein Atlas | STRADA |
| mTORC1 regulation | Inhibits mTORC1 through AMPK activation |
| Cell growth control | Regulates cell size through nutrient sensing |
| Energy homeostasis | Monitors cellular energy status (AMPK activation) |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
STRADA["STRADA"]
neurodegeneration["neurodegeneration"]
STRADA -->|"implicated_in"| neurodegeneration
style STRADA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning STRADA in their description or question text
No additional research found