STK25

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolSTK25
Nameserine/threonine kinase 25
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18

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