Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SOBP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SOBP |
| Full Name | Sine Oculis Binding Protein Homeobox |
| Chromosome | 10q21 |
| Protein Type | Transcription Factor |
| Function | SOBP is a homeodomain-containing transcription factor that regulates gene expression during neural development. |
| UniProt ID | Q9Y2X7 |
| NCBI Gene ID | 23098 |
| Ensembl ID | ENSG00000165633 |
| OMIM | 612485 |
| GeneCards | SOBP |
| Human Protein Atlas | SOBP |
| Inheritance Pattern | Autosomal Recessive / Dominant |
| Mechanism | Dysregulation of transcription affecting neuronal survival |
| Key Variants | Missense mutations in the homeodomain |
| Homeodomain | DNA-binding domain |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SOBP["SOBP"]
neurodegeneration["neurodegeneration"]
SOBP -->|"implicated_in"| neurodegeneration
style SOBP fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SOBP in their description or question text
No additional research found