gene

SNCBETA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SNCBETA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

SNCB Gene

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	SNCBETA
Full Name	Beta-Synuclein
Chromosome	5q35.2
Function	Beta-synuclein is a soluble cytoplasmic protein predominantly expressed in neurons
UniProt ID	Q9NQ88
NCBI Gene ID	6627
Ensembl ID	ENSG00000074370
OMIM	163570
GeneCards	SNCBETA
Human Protein Atlas	SNCBETA
Anti-aggregation Activity	Binds to alpha-synuclein and prevents its fibrillization into toxic oligomers and Lewy bodies<sup>[1]</sup>
Chaperone Function	Has molecular chaperone activity, protecting neurons from various stress conditions
Synaptic Function	Localizes to presynaptic terminals but does not aggregate under normal conditions
Lipid Binding	Binds to membranes but with lower affinity than alpha-synuclein
Association	Beta-synuclein pathology in MSA glial cytoplasmic inclusions<sup>[4]</sup>
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SNCBETA — AlphaFold Q9NQ88 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SNCB Gene

gene · 871 words

→

Pathway Diagram

graph TD
    SNCBETA["SNCBETA"]
    neurodegeneration["neurodegeneration"]
    SNCBETA -->|"implicated_in"| neurodegeneration
    style SNCBETA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SNCBETA in their description or question text

No additional research found