Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SNAP47: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SNAP47 |
| Protein Family | SNARE family |
| Protein Type | Receptor |
| Function | is a protein encoded by the SNAP47 gene. |
| Primary Expression | neurons throughout the brain, with particularly high expression in the hippocampus, [cortex](/brain |
| Subcellular Localization | Synaptic vesicles, presynaptic terminal |
| Molecular Weight | 47 kDa |
| Amino Acids | 355 aa |
| UniProt ID | [Q9BYF2](https://www.uniprot.org/uniprot/Q9BYF2) |
| Ensembl ID | ENSG00000143740 |
| GeneCards | SNAP47 |
| Human Protein Atlas | SNAP47 |
| Zero-layer | Centralionic layer with one arginine (R) residue |
| Flanking layers | 8 additional layers contributing to complex stability |
| Hydrophobic layers | Form the core of the SNARE bundle |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
SNAP47["SNAP47"]
neurodegeneration["neurodegeneration"]
SNAP47 -->|"implicated_in"| neurodegeneration
style SNAP47 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SNAP47 in their description or question text
No additional research found