Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SEPT2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SEPT2 |
| Full Name | Septin 2 |
| Chromosome | 2q37.3 |
| Function | encodes a critical member of the septin family of GTP-binding proteins that play essential roles in cellular organization, cytokinesis, membrane dynamics, and neuronal function. |
| Molecular Weight | 40.5 kDa |
| Amino Acids | 361 aa |
| Exons | 13 |
| UniProt ID | [Q15020](https://www.uniprot.org/uniprot/Q15020) |
| Ensembl ID | ENSG00000168385 |
| OMIM | 608679 |
| GeneCards | SEPT2 |
| Human Protein Atlas | SEPT2 |
| Octameric rods | The basic building block consisting of four different septin subunits |
| Filaments | Linear chains of octameric units |
| Rings | Circular structures observed at the cytokinetic furrow |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
SEPT2["SEPT2"]
neurodegeneration["neurodegeneration"]
SEPT2 -->|"implicated_in"| neurodegeneration
style SEPT2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SEPT2 in their description or question text
No additional research found