Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPL32: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RPL32 |
| Chromosome | 3p25.3 |
| Protein Family | L32E ribosomal family |
| Function | is a component of the 60S large ribosomal subunit and plays essential roles in protein synthesis, ribosome biogenesis, mitochondrial function, and cellular stress responses. |
| Primary Expression | Ubiquitous (high in bone marrow, liver, brain) |
| Molecular Weight | 15.8 kDa |
| Amino Acids | 137 aa |
| UniProt ID | P62999 |
| NCBI Gene ID | 6161 |
| Ensembl ID | ENSG00000137491 |
| GeneCards | RPL32 |
| Human Protein Atlas | RPL32 |
| Associated Diseases | neurodegeneration |
| Interactions | EIF4G2 |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["RPL32"]
N1["EIF4G2"]
N1 -->|"interacts with"| N0
N2["neurodegeneration"]
N0 -->|"implicated in"| N2
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 gene| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| EIF4G2 | interacts_with | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RPL32 in their description or question text
No additional research found