RIPK1

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolRIPK1
Namereceptor interacting serine/threonine kinase 1
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017].

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