RGS2

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolRGS2
Nameregulator of G protein signaling 2
Typeprotein-coding
Sourcemygene

Summary

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. [prov

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