RGS14

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolRGS14
Nameregulator of G protein signaling 14
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G b

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