Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RAB8B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RAB8B |
| Function | is a member of the Rab GTPase family that plays essential roles in exocytosis, ciliary trafficking, and neuronal function. |
| Primary Expression | various tissues with particularly high expression in: |
| Amino Acids | 212 aa |
| Ensembl ID | ENSG00000166147 |
| GeneCards | RAB8B |
| Human Protein Atlas | RAB8B |
| Brain | Enriched in neurons, particularly in synaptic regions |
| Olfactory epithelium | High levels in ciliated sensory neurons |
| Testis | Spermatogenesis and ciliary function |
| Kidney | Tubular cell function |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
RAB8B["RAB8B"]
neurodegeneration["neurodegeneration"]
RAB8B -->|"implicated_in"| neurodegeneration
style RAB8B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RAB8B in their description or question text
No additional research found