Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Parvalbumin Interneurons: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Activity-Dependent Maturation | involved_in | process | 0.95 |
| Postnatal Development | involved_in | process | 0.90 |
| activity-dependent maturation | promotes | process | 0.90 |
| Terminal Differentiation | involved_in | process | 0.85 |
| Activity-Dependent Maturation | participates_in | biological_process | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PGC1A | regulates | entity | 0.90 |
| Postnatal Molecular Switch | regulates | mechanism | 0.90 |
| Molecular Switch | regulates | mechanism | 0.90 |
| NEURONAL ACTIVITY | regulates | entity | 0.90 |
| Neural Activity | modulates | process | 0.88 |
| Postnatal Development | modulates | process | 0.85 |
| CORTEX | expressed_in | entity | 0.85 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Closed-loop tACS targeting EC-II parvalbumin interneurons to | 0.831 | Alzheimer's disease | Circuit-level neural dynamics in neurode |
| APOE4 astrocytes fail to supply sufficient cholesterol to pa | 0.500 | neuroscience | APOE4-driven lipid metabolism dysregulat |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Targeting Neural Oscillations for Cognitive Enhancement in Alzheimer’s Disease [PMID:40142358] | Federica Palacino, P. Manganotti, A. Ben | {'name': 'Medicina', 'volume': | 2025 | 0 |
| Impact of 40 Hz Transcranial Alternating Current Stimulation on Cerebral Tau Bur [PMID:34958021] | M. Dhaynaut, G. Sprugnoli, D. Cappon | {'name': "Journal of Alzheimer | 2021 | 0 |
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning Parvalbumin Interneurons in their description or question text
No additional research found