Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PUM2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | PUM2 |
| Full Name | Pumilio RNA Binding Family Member 2 |
| Chromosome | 2p24.1 |
| Function | is an RNA-binding protein that plays critical roles in post-transcriptional gene regulation, synaptic plasticity, memory formation, and neuronal survival [1](https://pubmed. |
| Amino Acids | 1064 aa |
| UniProt ID | Q9Y5Q8 |
| NCBI Gene ID | 23369 |
| Ensembl ID | ENSG00000090273 |
| OMIM | 607445 |
| GeneCards | PUM2 |
| Human Protein Atlas | PUM2 |
| Associated Diseases | Epilepsy, Intellectual Disability |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
PUM2["PUM2"]
neurodegeneration["neurodegeneration"]
PUM2 -->|"implicated_in"| neurodegeneration
style PUM2 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PUM2 in their description or question text
No additional research found