gene

PRKCE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PRKCE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

0Outgoing

1Incoming

0Experiments

0Debates

Summary

PRKCE Gene

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🧬 Gene Info

Gene Symbol	PRKCE
Full Name	protein kinase C epsilon
Chromosome	2p21
Protein Type	Kinase
Function	Protein kinase C epsilon (PKCε) is a novel PKC isoform member of the protein kinase C family of serine/threonine kinases.
Primary Expression	neurons, astrocytes, and some immune cells
UniProt ID	Q02156
NCBI Gene ID	5581
Ensembl ID	ENSG00000171793
OMIM	176975
GeneCards	PRKCE
Human Protein Atlas	PRKCE
Associated Diseases	neurodegeneration
Interactions	NPFF
KG Connections	1 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PRKCE — AlphaFold Q02156 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PRKCE Gene

gene · 1596 words

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Pathway Diagram

graph TD
    PRKCE["PRKCE"]
    style PRKCE fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff
    NPFF(["NPFF"])
    neurodegeneration["neurodegeneration"]

    NPFF -->|"activates"| PRKCE
    PRKCE -->|"implicated_in"| neurodegeneration

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#80cbc4,color:#e0e0e0
    class NPFF protein
    class neurodegeneration disease

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
NPFF	activates	protein	0.85

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PRKCE in their description or question text

No additional research found