gene

PRKAR1B

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about PRKAR1B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Gene page for PRKAR1B - regulatory subunit 1 beta of protein kinase A involved in synaptic plasticity, memory formation, and neurodegenerative diseases

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🧬 Gene Info

Gene Symbol	PRKAR1B
Full Name	Protein Kinase A Regulatory Subunit 1 Beta
Aliases	Gene page for PRKAR1B
Chromosome	7p22.1
Primary Expression	Hippocampus, Cerebral Cortex, Cerebellum, Striatum, Peripheral neurons
Subcellular Localization	, anchoring, and activation kinetics of the catalytic subunits. In the brain, PRKAR1B is predominantly expressed in neur
Molecular Weight	46 kDa
Amino Acids	415 aa
Exons	11
UniProt ID	P31321
NCBI Gene ID	5577
Ensembl ID	ENSG00000188191
OMIM	176911
GeneCards	PRKAR1B
Human Protein Atlas	PRKAR1B
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PRKAR1B — AlphaFold P31321 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PRKAR1B — Protein Kinase A Regulatory Subunit 1 Beta

gene · 1734 words

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Pathway Diagram

graph TD
    PRKAR1B["PRKAR1B"]
    neurodegeneration["neurodegeneration"]
    PRKAR1B -->|"implicated_in"| neurodegeneration
    style PRKAR1B fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning PRKAR1B in their description or question text

No additional research found