Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PI3K_Akt_signaling: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| microglial_M2_polarization | regulates | mechanism | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GPR32 | activates | protein | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| CD44-Mediated Src/PI3K/Akt Signaling Cascade | 0.470 | neuroinflammation | What molecular mechanisms mediate SPP1-i |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-01 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning PI3K_Akt_signaling in their description or question text
No additional research found