Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PEX10: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Peroxisome Biogenesis Factor 10 - essential peroxin for peroxisome biogenesis, matrix protein import, and peroxisomal quality control; mutations cause Zellweger spectrum disorders and are implicated in Alzheimer's and Parkinson's disease
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| Gene Symbol | PEX10 |
| Full Name | Peroxisome Biogenesis Factor 10 |
| Protein Family | RING finger protein family |
| Function | is a peroxisomal membrane protein essential for peroxisome biogenesis and peroxisomal matrix protein import. |
| Subcellular Localization | Peroxisomal membrane |
| Molecular Weight | 38 kDa |
| Amino Acids | 335 aa |
| UniProt ID | O60313 |
| GeneCards | PEX10 |
| Human Protein Atlas | PEX10 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
PEX10["PEX10"]
neurodegeneration["neurodegeneration"]
PEX10 -->|"implicated_in"| neurodegeneration
style PEX10 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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Scientific publications cited in analyses involving this entity
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PEX10 in their description or question text
No additional research found