PDGFB

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolPDGFB
Nameplatelet derived growth factor subunit B
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental proce

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