Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PDE4A, PDE4B, PDE4D: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Target | Relation | Type | Str |
|---|---|---|---|
| neuroinflammation | promoted: PDE4 Inhibition as Inflammatory Reset for PD Oligodendrocytes | disease | 0.58 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| PDE4 Inhibition as Inflammatory Reset for PD Oligodendrocyte | 0.749 | neuroinflammation | How do oligodendrocytes initiate neuroin |
Scientific analyses that reference this entity
neuroinflammation | 2026-04-13 | 2 hypotheses Top: 0.831
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| Molecular docking analysis of aminophylline binding targets | exploratory | depression | 0.800 | 0.00 | in silico molecular docking | proposed | N/A |
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning PDE4A, PDE4B, PDE4D in their description or question text
No additional research found