gene

PANK3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PANK3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for PANK3 Gene

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	PANK3
Full Name	Pantothenate Kinase 3
Chromosome	5q31.1
Function	encodes a protein of 445 amino acids with a molecular weight of approximately 48 kDa.
Molecular Weight	48 kDa
Amino Acids	445 aa
Exons	14
Ensembl ID	ENSG00000142082
GeneCards	PANK3
Human Protein Atlas	PANK3
PANK family	Four isoforms (PANK1α, PANK1β, PANK2, PANK3, PANK4) in humans
Conservation	Evolutionarily conserved from bacteria to humans
Duplication events	Multiple gene duplication events during vertebrate evolution
Functional specialization	Different isoforms acquired tissue-specific expression
Magnesium-dependent	Requires Mg²⁺ as a cofactor
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PANK3 — Pantothenate Kinase 3

gene · 1318 words

→

Pathway Diagram

flowchart TD
    N0["PANK3"]
    N1["AKT"]
    N1 -->|"regulates"| N0
    N2["neurodegeneration"]
    N0 -->|"implicated in"| N2

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N1 gene

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PANK3 in their description or question text

No additional research found