concept

OTUD6A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about OTUD6A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

18Connections

0Hypotheses

0Analyses

16Outgoing

2Incoming

0Experiments

0Debates

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💡 Concept Info

Name	OTUD6A
Key Genes/Proteins	ACTG1, Ubiquitin
Related Diseases	Parkinson's Disease, Parkinson'S Disease
Related Pathways	TP53-dependent apoptotic pathway, ubiquitin-proteasome

Pathway Diagram

graph TD
    OTUD6A[OTUD6A]
    OTUD6A -->|promotes| dopaminergic_neuronal_degenera[dopaminergic neuronal degeneration]
    OTUD6A -->|interacts| ACTG1[ACTG1]
    OTUD6A -->|promotes| Dopaminergic_Neuronal_Degenera[Dopaminergic Neuronal Degeneration]
    OTUD6A -->|drives| Parkinson_s_Disease[Parkinson's Disease]
    OTUD6A -->|promotes| Parkinson_S_Disease[Parkinson'S Disease]
    OTUD6A -->|degrades| Ubiquitin[Ubiquitin]
    OTUD6A -->|upregulates| dopaminergic_neurons[dopaminergic neurons]
    ACTG1 -->|targets| OTUD6A

Outgoing (16)

Target	Relation	Type	Str
Ubiquitin	degrades	protein	0.95
Parkinson'S Disease	promotes	disease	0.95
Parkinson's Disease	drives	disease	0.95
ACTG1	associated_with	protein	0.95
dopaminergic neuronal degeneration	promotes	process	0.95
ACTG1	interacts_with	gene	0.95
ACTG1	degrades	protein	0.95
Dopaminergic Neuronal Degeneration	promotes	process	0.95
ACTG1	interacts_with	protein	0.90
Parkinson'S Disease	upregulates	disease	0.90
dopaminergic neurons	upregulates	cell_type	0.90
Parkinson'S Disease	therapeutic_target	disease	0.85
TP53-dependent apoptotic pathway	activates	pathway	0.85
Parkinson's Disease	therapeutic_target	disease	0.80
neurons	expressed_in	cell_type	0.60
ubiquitin-proteasome	participates_in	pathway	0.60

Incoming (2)

Source	Relation	Type	Str
ACTG1	targets	gene	0.60
ACTG1	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning OTUD6A in their description or question text

No additional research found