entity

OGA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about OGA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections
3Hypotheses
1Analyses
0Outgoing
1Incoming
0Experiments
1Debates

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Wiki Pages (10)

Knowledge base pages for this entity

Canonical Page

Eli Lilly and Company — Neuroscience and Tauopathy Programs

company · 636 words

O-GlcNAcase (OGA) Inhibitor Landscape — Programs, Mechanisms, Companies

therapeutic · 3763 words

AL-207 — Alectos Therapeutics OGA Inhibitor

therapeutic · 2328 words

ASN90 (Asceneuron OGA Inhibitor)

therapeutic · 2023 words

MGEA5 — O-GlcNAcase (OGA)

gene · 1779 words

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)

disease · 1759 words

Outgoing (0)

TargetRelationTypeStr
No outgoing edges

Incoming (1)

SourceRelationTypeStr
MGEA5 (OGA)co_associated_withgene0.30

Targeting Hypotheses (3)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Blood Monocyte Epigenetic Signature as Surrogate for Microgl 0.520 biomarkers What biomarkers can reliably detect micr
Selective OGA Inhibition as 'Tau Stabilization' Strategy Wit 0.458 neurodegeneration Which tau PTMs are both disease-specific
AQP4 Water Channel Normalization as Surrogate Marker and The 0.105 neurodegeneration Neuroinflammation Biomarker Panel for Ea

Mentioning Analyses (1)

Scientific analyses that reference this entity

Which tau PTMs are both disease-specific and druggable with selective small mole

neurodegeneration | 2026-04-13 | 2 hypotheses Top: 0.484

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (1)

Multi-agent debates referencing this entity

The debate highlighted promising PTMs like K280 acetylation and O-GlcNAcylation

closed · Rounds: 4 · Score: 0.65 · 2026-04-13

Related Research

Hypotheses and analyses mentioning OGA in their description or question text

No additional research found