Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEURONAL PLASTICITY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEURONAL PLASTICITY |
graph TD
NEURONAL_PLASTICITY[NEURONAL PLASTICITY]
NEURONAL_PLASTICITY -->|mediates| Antidepressant_Action[Antidepressant Action]
SEROTONIN[SEROTONIN] -->|regulates| NEURONAL_PLASTICITY
Serotonin[Serotonin] -->|regulates| NEURONAL_PLASTICITY
Serotonylation[Serotonylation] -->|regulates| NEURONAL_PLASTICITY
Thyroid_Hormones[Thyroid Hormones] -->|modulates| NEURONAL_PLASTICITY
BDNF[BDNF] -->|regulates| NEURONAL_PLASTICITY
antidepressant_treatments[antidepressant treatments] -->|stimulates| NEURONAL_PLASTICITY
parvalbumin_expressing_neurons[parvalbumin-expressing neurons] -->|drives| NEURONAL_PLASTICITY| Target | Relation | Type | Str |
|---|---|---|---|
| Antidepressant Action | mediates | mechanism | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| 31163285 | regulate | paper | 0.90 |
| SEROTONIN | regulates | entity | 0.90 |
| Serotonin | involved_in | entity | 0.85 |
| Thyroid Hormones | modulates | compound | 0.85 |
| Serotonin | regulates | compound | 0.85 |
| Serotonylation | regulates | process | 0.85 |
| BDNF | promotes | gene | 0.85 |
| BDNF | regulates | protein | 0.85 |
| parvalbumin-expressing neurons | drives | cell_type | 0.80 |
| antidepressant treatments | stimulates | process | 0.80 |
| DEPRESSION | impairs | disease | 0.70 |
| BDNF | regulates | protein | 0.70 |
| BDNF | activates | protein | 0.70 |
| BDNF | involved_in | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NEURONAL PLASTICITY in their description or question text
No additional research found