Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NTF5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | NTF5 |
| Full Name | Neurotrophin 5 |
| Aliases | Neurotrophin-5 |
| Chromosome | 19q13.33 |
| Function | is a member of the neurotrophin family of growth factors that plays critical roles in neuronal survival, development, and function [1]. |
| Primary Expression | Brain (cortex, hippocampus), peripheral nerves, Schwann cells |
| Molecular Weight | 28 kDa |
| Amino Acids | 254 aa |
| UniProt ID | P34130 |
| NCBI Gene ID | 4909 |
| Ensembl ID | ENSG00000185666 |
| OMIM | 162680 |
| GeneCards | NTF5 |
| Human Protein Atlas | NTF5 |
| Activity-dependent elements | CREB (cAMP response element-binding) binding sites |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
NTF5["NTF5"]
neurodegeneration["neurodegeneration"]
NTF5 -->|"implicated_in"| neurodegeneration
style NTF5 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NTF5 in their description or question text
No additional research found