gene

NOP56

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about NOP56: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for NOP56 Gene

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🧬 Gene Info

Gene Symbol	NOP56
Protein Family	Nucleolar protein family
Function	Core snoRNP component (box C/D snoRNPs)
Molecular Weight	66 kDa
UniProt ID	O00447
GeneCards	NOP56
Human Protein Atlas	NOP56
Molecular weight	~66 kDa
Cellular localization	Nucleolus
Ribosome biogenesis	Pre-rRNA processing and modification
snoRNP assembly	Forms complex with NOP58, fibrillarin, and snoRNAs
RNA methyltransferases	Provides scaffold for 2'-O-methylation
Neuronal homeostasis	Essential for neuronal survival
Repeat length	Normal < 15, pathogenic > 18-500+
Inheritance	Autosomal dominant
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: NOP56 — AlphaFold O00447 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NOP56 Gene

gene · 700 words

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Pathway Diagram

graph TD
    NOP56["NOP56"]
    neurodegeneration["neurodegeneration"]
    NOP56 -->|"implicated_in"| neurodegeneration
    style NOP56 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning NOP56 in their description or question text

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