entity

NMJ

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NMJ: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

5Hypotheses

2Analyses

0Outgoing

0Incoming

0Experiments

2Debates

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Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (5)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
CCL2-CCR2 Driven Macrophage Infiltration Selectively Strips	0.682	ALS	CCL2-CCR2 Axis at NMJ: Mechanism of Sele
CCL2-CCR2 myeloid signaling as a selective driver of fast-fa	0.626	neurodegeneration	CCL2-CCR2 Axis at NMJ: Mechanism of Sele
mutant FUS effects split between motor-neuron intrinsic stre	0.626	neurodegeneration	Cell-Autonomous vs Non-Cell-Autonomous M
Cell-state stratification is required to resolve CCL2-CCR2 A	0.612	neurodegeneration	CCL2-CCR2 Axis at NMJ: Mechanism of Sele
Perturbation-first validation should precede therapeutic cla	0.608	neurodegeneration	CCL2-CCR2 Axis at NMJ: Mechanism of Sele