NLRP7

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNLRP7
NameNLR family pyrin domain containing 7
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing resul

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This is an externally resolved entity

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