gene

NHLRC2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NHLRC2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections

0Hypotheses

0Analyses

8Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for NHLRC2 Gene

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	NHLRC2
Full Name	NHL Repeat Containing 2
Chromosome	10q26.3
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	most tissues:
Amino Acids	395 aa
Pathways	p53 Signaling Pathway
UniProt ID	Q8N8Y6
NCBI Gene ID	153768
Ensembl ID	ENSG00000155438
GeneCards	NHLRC2
Human Protein Atlas	NHLRC2
Associated Diseases	Fibrosis, Neurodegeneration, Skeletal Muscle Atrophy
KG Connections	8 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: NHLRC2 — AlphaFold Q8N8Y6 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

NHLRC2 Gene

gene · 510 words

→

NHLRC2 Protein — NHL Repeat Containing 2

protein · 815 words

→

Pathway Diagram

graph TD
    NHLRC2["NHLRC2"]
    Skeletal_Muscle_Atrophy{"Skeletal Muscle Atrophy"}
    NHLRC2 -->|"associated_with"| Skeletal_Muscle_Atrophy
    Neurodegeneration{"Neurodegeneration"}
    NHLRC2 -->|"causes"| Neurodegeneration
    Fibrosis{"Fibrosis"}
    NHLRC2 -->|"causes"| Fibrosis
    Autophagy["Autophagy"]
    NHLRC2 -->|"participates_in"| Autophagy
    Oxidative_Stress["Oxidative Stress"]
    NHLRC2 -->|"participates_in"| Oxidative_Stress
    Apoptosis["Apoptosis"]
    NHLRC2 -->|"participates_in"| Apoptosis
    p53_Signaling_Pathway(["p53 Signaling Pathway"])
    NHLRC2 -->|"participates_in"| p53_Signaling_Pathway
    Immune_Response(["Immune Response"])
    NHLRC2 -->|"associated_with"| Immune_Response
    NEURODEGENERATION["NEURODEGENERATION"]
    NHLRC2 -->|"causes"| NEURODEGENERATION
    AND["AND"]
    NHLRC2 -->|"associated_with"| AND
    IMMUNE_RESPONSE(["IMMUNE RESPONSE"])
    NHLRC2 -->|"associated_with"| IMMUNE_RESPONSE
    neurodegeneration["neurodegeneration"]
    NHLRC2 -->|"implicated_in"| neurodegeneration

Outgoing (8)

Target	Relation	Type	Str
Skeletal Muscle Atrophy	associated_with	disease	0.70
Neurodegeneration	causes	disease	0.65
Fibrosis	causes	disease	0.65
Immune Response	associated_with	pathway	0.60
p53 Signaling Pathway	participates_in	pathway	0.60
NEURODEGENERATION	causes	gene	0.60
AND	associated_with	gene	0.60
IMMUNE RESPONSE	associated_with	pathway	0.50

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NHLRC2 in their description or question text

No additional research found