gene

NCX3

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about NCX3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

NCX3 (SLC8A3) Gene

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🧬 Gene Info

Gene Symbol	NCX3
Full Name	Sodium Calcium Exchanger 3
Aliases	NCX3 (SLC8A3)
Chromosome	20p13
Function	NCX3 (SLC8A3) encodes the sodium-calcium exchanger 3, a unique isoform of the NCX family with distinctive expression patterns and functional properties
Primary Expression	Brain, Skeletal muscle, Heart, Retina
Molecular Weight	~108 kDa
Amino Acids	932 aa
UniProt ID	Q9M819
NCBI Gene ID	6578
Ensembl ID	ENSG00000170088
OMIM	607858
GeneCards	NCX3
Human Protein Atlas	NCX3
Skeletal muscle	Highest expression in fast-twitch skeletal muscle fibers
Databases	GeneCards HPA STRING

🔮 Predicted Structure: NCX3 — AlphaFold Q9M819 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NCX3 (SLC8A3) Gene

gene · 1226 words

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Pathway Diagram

graph TD
    NCX3["NCX3"]
    neurodegeneration["neurodegeneration"]
    NCX3 -->|"implicated_in"| neurodegeneration
    style NCX3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning NCX3 in their description or question text

No additional research found