gene

MOB1A

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about MOB1A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🧬 Gene Info

Gene Symbol	MOB1A
Chromosome	4q21.1
Protein Type	Kinase
Function	is a key regulatory protein in the Hippo signaling pathway, which controls organ size by regulating cell proliferation, apoptosis, and stem cell self-renewal[@hergovich2021].
GeneCards	MOB1A
Human Protein Atlas	MOB1A
MST1/MST2	Upstream kinase partners
LATS1/LATS2	Downstream effector kinases
Hippo Pathway	Core signaling cascade
YAP/TAZ	Transcriptional coactivator substrates
MOB1B	Paralogous protein with overlapping functions
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

MOB1A Gene

gene · 603 words

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Pathway Diagram

graph TD
    MOB1A["MOB1A"]
    neurodegeneration["neurodegeneration"]
    MOB1A -->|"implicated_in"| neurodegeneration
    style MOB1A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

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Experiments (0)

Experimental studies targeting or related to this entity

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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

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Related Research

Hypotheses and analyses mentioning MOB1A in their description or question text

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