protein

MITOFUSIN1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about MITOFUSIN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🔬 Protein Info

Gene Symbol	MITOFUSIN1
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	</strong></td><td>Mitochondrial Outer Membrane</td></tr>
GeneCards	MITOFUSIN1
Human Protein Atlas	MITOFUSIN1
N-terminal GTPase domain	Catalyzes GTP hydrolysis for membrane fusion
Middle domain	Involved in protein-protein interactions
Two transmembrane helices	Anchor protein in mitochondrial outer membrane
C-terminal GTPase effector domain (GED)	Regulates GTPase activity and membrane tethering
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Mitofusin-1 Protein

protein · 876 words

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Pathway Diagram

graph TD
    MITOFUSIN1["MITOFUSIN1"]
    neurodegeneration["neurodegeneration"]
    MITOFUSIN1 -->|"implicated_in"| neurodegeneration
    style MITOFUSIN1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

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Related Research

Hypotheses and analyses mentioning MITOFUSIN1 in their description or question text

No additional research found