gene

LAMTOR2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LAMTOR2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

3Connections

0Hypotheses

0Analyses

1Outgoing

2Incoming

0Experiments

0Debates

Summary

Page for LAMTOR2 Gene

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🧬 Gene Info

Gene Symbol	MLST8
Full Name	MTOR Associated Protein, LST8 Homolog
Aliases	LAMTOR2
Protein Family	LST8/MLST8 family
Function	is a critical component of both mTORC1 and mTORC2 complexes and plays important roles in neurodegenerative diseases.
Primary Expression	Ubiquitous; highest in brain, heart, skeletal muscle
Subcellular Localization	Lysosomal membrane, cytoplasm
Molecular Weight	36 kDa
Pathways	MTOR, mtor, mTOR, signaling: ### Ragulator Complex, MAPK
UniProt ID	Q8BXR0
NCBI Gene ID	84916
GeneCards	MLST8
Human Protein Atlas	MLST8
Associated Diseases	neurodegeneration
Interactions	BCLAF1, VSIG2
KG Connections	3 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: LAMTOR2 — AlphaFold Q8BXR0 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

LAMTOR2 Gene

gene · 1242 words

→

LAMTOR2 Protein

protein · 700 words

→

Pathway Diagram

graph TD
    LAMTOR2["LAMTOR2"]
    BCR(["BCR"])
    VSIG2(["VSIG2"])
    BCLAF1(["BCLAF1"])
    neurodegeneration["neurodegeneration"]

    LAMTOR2 -->|"regulates"| BCR
    VSIG2 -->|"interacts with"| LAMTOR2
    BCLAF1 -->|"interacts with"| LAMTOR2
    LAMTOR2 -->|"implicated in"| neurodegeneration

    style LAMTOR2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style BCR fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
    style VSIG2 fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
    style BCLAF1 fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
    style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff

Outgoing (1)

Target	Relation	Type	Str
BCR	regulates	protein	0.80

Incoming (2)

Source	Relation	Type	Str
VSIG2	interacts_with	protein	0.80
BCLAF1	interacts_with	protein	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning LAMTOR2 in their description or question text

No additional research found