gene

KCNMB3

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about KCNMB3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for KCNMB3

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🧬 Gene Info

Gene Symbol	KCNMB3
Full Name	Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 3
Chromosome	22q12.1
Protein Type	Channel
Function	is a voltage-gated potassium channel with high conductance (100-200 pS) that is activated by both membrane depolarization and intracellular calcium[@structure2008].
Primary Expression	various tissues including brain, smooth muscle, and endocrine cells, where they play crucial roles in regulating neuronal excitability, neurotransmitt
Molecular Weight	31 kDa
Amino Acids	281 aa
UniProt ID	Q9NS88
NCBI Gene ID	8912
Ensembl ID	ENSG00000143001
GeneCards	KCNMB3
Human Protein Atlas	KCNMB3
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNMB3 — AlphaFold Q9NS88 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KCNMB3

gene · 844 words

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Pathway Diagram

graph TD
    KCNMB3["KCNMB3"]
    neurodegeneration["neurodegeneration"]
    KCNMB3 -->|"implicated_in"| neurodegeneration
    style KCNMB3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KCNMB3 in their description or question text

No additional research found