gene

KCNA10

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNA10: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections

0Hypotheses

0Analyses

3Outgoing

2Incoming

0Experiments

0Debates

Summary

Potassium Voltage-Gated Channel Subfamily A Member 10 - Kv1.6 channel subunit with roles in renal potassium secretion, inner ear function, and neuronal excitability

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	KCNA10
Full Name	Potassium Voltage-Gated Channel Subfamily A Member 10
Aliases	Page for KCNA10 Protein
Chromosome	1p21.3
Protein Type	Channel
Function	is a potassium voltage-gated channel gene located at chromosome 1p21.
Primary Expression	non-neuronal tissues, KCNA10's role in calcium signaling, oxidative stress responses, and neuroimmune interactions makes it relevant to understanding
Molecular Weight	56 kDa
Amino Acids	499 aa
UniProt ID	Q9NSC2
NCBI Gene ID	3744
GeneCards	KCNA10
Human Protein Atlas	KCNA10
S1-S4 voltage sensor domain	S4 contains positively charged residues that sense membrane potential changes
S5-S6 pore domain (P loop)	Forms the ion selectivity filter with signature TXVGYG motif
Associated Diseases	neurodegeneration
Interactions	KCNA4B
KG Connections	5 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KCNA10 — AlphaFold Q9NSC2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

KCNA10 Gene

gene · 1905 words

→

KCNA10 Protein - Kv1.10 Potassium Channel

protein · 719 words

→

Pathway Diagram

graph TD
    KCNA10["KCNA10"]
    KCNA4B["KCNA4B"]
    KCNA10 -->|"binds"| KCNA4B
    vestibular_system["vestibular_system"]
    KCNA10 -->|"participates in"| vestibular_system
    hearing["hearing"]
    KCNA10 -->|"participates in"| hearing
    neurodegeneration["neurodegeneration"]
    KCNA10 -->|"implicated in"| neurodegeneration
    KCNA4B -->|"activates"| KCNA10
    BMP_2["BMP-2"]
    BMP_2 -->|"upregulates"| KCNA10
    style KCNA10 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (3)

Target	Relation	Type	Str
KCNA4B	binds	gene	0.80
vestibular_system	participates_in	process	0.80
hearing	participates_in	process	0.70

Incoming (2)

Source	Relation	Type	Str
KCNA4B	activates	gene	0.80
BMP-2	upregulates	protein	0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KCNA10 in their description or question text

No additional research found