protein

JPH3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about JPH3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

0Debates

Summary

Page for JPH3 Protein

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🔬 Protein Info

Gene Symbol	JPH3
Full Name	Junctophilin 3
Chromosome	16q24.3
Function	JPH3 encodes Junctophilin-3, a membrane protein that plays critical roles in forming and maintaining junctional membrane complexes (JMCs) between the plasma membrane and the endoplasmic reticulum (ER)
Primary Expression	neurons and may protect against excitotoxicity
Molecular Weight	75 kDa
UniProt ID	Q9Y2W5
NCBI Gene ID	57338
Ensembl ID	ENSG00000125900
OMIM	605714
GeneCards	JPH3
Human Protein Atlas	JPH3
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: JPH3 — AlphaFold Q9Y2W5 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

JPH3 Gene

gene · 1335 words

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JPH3 Protein

protein · 636 words

→

Pathway Diagram

graph TD
    JPH3["JPH3"]
    neurodegeneration["neurodegeneration"]
    JPH3 -->|"implicated_in"| neurodegeneration
    style JPH3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning JPH3 in their description or question text

No additional research found