protein

IPTC

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about IPTC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Inverted Formin 2 (INF2)

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🔬 Protein Info

Gene Symbol	IPTC
Full Name	Inverted Formin 2 (INF2)
Chromosome	14q11.2.
Protein Type	Protein
Function	INF2 is a unique formin protein with dual roles:
Subcellular Localization	the FH2 domain or adjacent regulatory regions, disrupting actin nucleation capacity or altering protein stability. These
UniProt ID	Search UniProt
GeneCards	IPTC
Human Protein Atlas	IPTC
Formin Family	mDia1, mDia2, INF1
Cytoskeletal Regulators	Cdc42, Rac1, RhoA
Mitochondrial Dynamics	DRP1, OPA1, MFN2
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: IPTC — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Inverted Formin 2 (INF2)

protein · 632 words

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Pathway Diagram

graph TD
    IPTC["IPTC"]
    neurodegeneration["neurodegeneration"]
    IPTC -->|"implicated_in"| neurodegeneration
    style IPTC fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning IPTC in their description or question text

No additional research found