gene

IL29

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL29: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	IL29
Chromosome	19q13.2
Function	is a cytokine gene encoding a Type III interferon that plays crucial roles in antiviral immunity, immune modulation, and neuroinflammation.
Amino Acids	200 aa
Exons	5
Pathways	JAK-STAT Pathway
Ensembl ID	ENSG00000184916
GeneCards	IL29
Human Protein Atlas	IL29
Cell Types	Expressed by neurons, microglia, and astrocytes in response to viral infection
Regional Distribution	Highest expression in hippocampus, cortex, and basal ganglia
Induction	RequiresPattern Recognition Receptor (PRR) signaling via RIG-I/MDA5 or TLR3
Antiviral	OAS, MX, IFITM, viperin
Immunomodulatory	PD-L1, MHC-I, IL-12 antagonist
Antiproliferative	p21, p27, TRAIL
Associated Diseases	neurodegeneration
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

il29

gene · 1239 words

→

Pathway Diagram

graph TD
    IL29["IL29"]
    neurodegeneration["neurodegeneration"]
    IL29 -->|"implicated_in"| neurodegeneration
    style IL29 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning IL29 in their description or question text

No additional research found