therapeutic

Ibudilast

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Ibudilast: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1Connections

0Hypotheses

0Analyses

0Outgoing

1Incoming

0Experiments

0Debates

Summary

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💊 Therapeutic Info

Name	Ibudilast

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Ibudilast

therapeutic · 2773 words

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Pathway Diagram

flowchart TD
    Ibudilast["Ibudilast"] -->|"references"| NLRP3["NLRP3"]
    FINGOLIMOD["FINGOLIMOD"] -->|"associated with"| IBUDILAST["IBUDILAST"]
    Fingolimod["Fingolimod"] -->|"treats"| Ischemic_Brain_Injury["Ischemic Brain Injury"]
    Fingolimod["Fingolimod"] -.->|"inhibits"| HMGB1_TLR4_NF__B_Signaling_Pat["HMGB1/TLR4/NF-kappaB Signaling Pathway"]
    Fingolimod["Fingolimod"] -.->|"downregulates"| IL_1_["IL-1beta"]
    Fingolimod["Fingolimod"] -.->|"downregulates"| IL_6["IL-6"]
    NLRP3["NLRP3"] -->|"associated with"| Inflammation["Inflammation"]
    NLRP3["NLRP3"] -->|"activates"| Inflammasome["Inflammasome"]
    NLRP3["NLRP3"] -.->|"inhibits"| Inflammation["Inflammation"]
    NLRP3["NLRP3"] -.->|"inhibits"| Als["Als"]
    style Ibudilast fill:#6d3000,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0
    style NLRP3 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style FINGOLIMOD fill:#6d3000,stroke:#333,color:#e0e0e0
    style IBUDILAST fill:#6d3000,stroke:#333,color:#e0e0e0
    style Fingolimod fill:#6d3000,stroke:#333,color:#e0e0e0
    style Ischemic_Brain_Injury fill:#ef5350,stroke:#333,color:#e0e0e0
    style HMGB1_TLR4_NF__B_Signaling_Pat fill:#1b5e20,stroke:#333,color:#e0e0e0
    style IL_1_ fill:#006494,stroke:#333,color:#e0e0e0
    style IL_6 fill:#006494,stroke:#333,color:#e0e0e0
    style Inflammation fill:#ef5350,stroke:#333,color:#e0e0e0
    style Inflammasome fill:#1b5e20,stroke:#333,color:#e0e0e0
    style Als fill:#ef5350,stroke:#333,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (1)

Source	Relation	Type	Str
FINGOLIMOD	associated_with	drug	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning Ibudilast in their description or question text

No additional research found