Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Huntington disease: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| BDNF | inhibits | protein | 0.90 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Astrocytes | contributes_to | cell_type | 0.90 |
| SQSTM1 | biomarker_for | protein | 0.85 |
| CASP6 | associated_with | protein | 0.85 |
| LYSOSOMAL PROTEINS | causes | protein | 0.80 |
| SQSTM1 S-acylation | associated_with | mechanism | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-03 | 14 hypotheses Top: 0.803
neurodegeneration | 2026-04-02 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.95 · 2026-04-03
closed · Rounds: 4 · Score: 0.90 · 2026-04-02
Hypotheses and analyses mentioning Huntington disease in their description or question text
No additional research found