Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HSPB6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | HSPB6 |
| Full Name | Heat Shock Protein Beta 6 |
| Chromosome | 19p13.13 |
| Function | HSPB6/Hsp20 performs several critical cellular functions: |
| Primary Expression | neurons and glial cells, with increased expression under stress conditions including ischemia and oxidative stress |
| Molecular Weight | 17 kDa |
| Amino Acids | 160 aa |
| UniProt ID | O14920 |
| NCBI Gene ID | 126328 |
| Ensembl ID | ENSG00000104888 |
| OMIM | 609336 |
| GeneCards | HSPB6 |
| Human Protein Atlas | HSPB6 |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
HSPB6["HSPB6"]
neurodegeneration["neurodegeneration"]
HSPB6 -->|"implicated_in"| neurodegeneration
style HSPB6 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HSPB6 in their description or question text
No additional research found