Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HOXD13: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Comprehensive review of HOXD13 gene, a homeobox transcription factor critical for limb development and implicated in neurodegenerative disease pathogenesis
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| Gene Symbol | HOXD13 |
| Full Name | Homeobox D13 |
| Chromosome | 2q31.1 |
| Protein Family | Homeobox, HOXD family |
| Protein Type | Transcription Factor |
| Function | is a human gene located on chromosome 2q31. |
| Primary Expression | Cortex, Hippocampus, Cerebellum, Spinal cord, Limb buds |
| Amino Acids | 312 aa |
| UniProt ID | P09030 |
| NCBI Gene ID | 3239 |
| Ensembl ID | ENSG00000128714 |
| OMIM | 142989 |
| GeneCards | HOXD13 |
| Human Protein Atlas | HOXD13 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
HOXD13["HOXD13"]
neurodegeneration["neurodegeneration"]
HOXD13 -->|"implicated_in"| neurodegeneration
style HOXD13 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HOXD13 in their description or question text
No additional research found