Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HNRPM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | HNRPM |
| Full Name | Heterogeneous Nuclear Ribonucleoprotein M |
| Chromosome | 19p13.2 |
| Function | is a member of the hnRNP family of RNA-binding proteins that plays essential roles in RNA processing, including alternative splicing, mRNA stability, and translation regulation. |
| Primary Expression | neurons and astrocytes; lower expression in microglia - Subcellular Localization: Predominantly nuc |
| Subcellular Localization | **: Predominantly nuclear; cytoplasmic localization increases with cellular stress |
| Molecular Weight | Approximately 77 kDa |
| Amino Acids | 90 aa |
| Exons | 19 |
| UniProt ID | [P52272](https://www.uniprot.org/uniprot/P52272) |
| Ensembl ID | ENSG00000199787 |
| OMIM | 160994 |
| GeneCards | HNRPM |
| Human Protein Atlas | HNRPM |
| Genomic Size | Spans approximately 22 kb of genomic DNA |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
HNRPM["HNRPM"]
neurodegeneration["neurodegeneration"]
HNRPM -->|"implicated_in"| neurodegeneration
style HNRPM fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HNRPM in their description or question text
No additional research found