gene

HNRNPA3

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about HNRNPA3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

HNRNPA3 gene - RNA processing in ALS and neurodegeneration

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🧬 Gene Info

Gene Symbol	HNRNPA3
Full Name	Heterogeneous Nuclear Ribonucleoprotein A3
Aliases	HNRNPA3 gene
Chromosome	10q12
Function	RNA recognition motifs (RRMs): Two RRMs (RRM1 and RRM2) for RNA binding
Amino Acids	378 aa
UniProt ID	P51991
NCBI Gene ID	10136
Ensembl ID	ENSG00000169020
OMIM	605017
GeneCards	HNRNPA3
Human Protein Atlas	HNRNPA3
GU-rich sequences	Binds specifically to GU-rich RNA motifs
Pre-mRNA interactions	Associates with splicing machinery
mRNA trafficking	Participates in mRNA localization
Associated Diseases	neurodegeneration
Databases	GeneCards HPA STRING

🔮 Predicted Structure: HNRNPA3 — AlphaFold P51991 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

HNRNPA3 Gene

gene · 1515 words

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Pathway Diagram

graph TD
    HNRNPA3["HNRNPA3"]
    neurodegeneration["neurodegeneration"]
    HNRNPA3 -->|"implicated_in"| neurodegeneration
    style HNRNPA3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning HNRNPA3 in their description or question text

No additional research found