Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HEXDC3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | HDDX3 |
| Full Name | HEXDC3 |
| Aliases | HEXA [@platt2020] |
| Chromosome | 15q24.2 [@conway2004] |
| Protein Type | Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | both cytoplasmic and potentially nuclear compartments, though subcellular distribution may vary depending on post-transl |
| Amino Acids | 529 aa |
| Exons | 14 |
| UniProt ID | Search UniProt |
| NCBI Gene ID | 284161 |
| Ensembl ID | ENSG00000146243 |
| GeneCards | HDDX3 |
| Human Protein Atlas | HDDX3 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
HEXDC3["HEXDC3"]
neurodegeneration["neurodegeneration"]
HEXDC3 -->|"implicated_in"| neurodegeneration
style HEXDC3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HEXDC3 in their description or question text
No additional research found